We developed the first diatom-based transfer function for the east coast of North America to reconstruct former sea levels based upon the relationship between diatom assemblage and elevation. Results imply that this is possible to a precision of ±0.08 m, superior to most similar studies from temperate, mid-latitude environments. The transfer function is used to construct a relative sea-level curve from fossil assemblages from Salvo, North Carolina. These results suggest a sea-level rise of 0.7 m over the last c. 150 years, at an average of c. 3.7 mm year−1. This is consistent with existing sea-level data, and illustrates the utility of the transfer function approach.