Cerebral Ischemic Involvement in Vogt-Koyanagi-Harada Disease

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• 作者：Raffaella Vergaro ; MD^a ; ^{r.vergaro@gmail.com" class="auth_mail} ; Duccio Maria Cordelli ; MD^a ; Angela Miniaci ; MD^b ; Davide Tassinari ; MD^b ; Luca Spinardi ; MD^c ; Andrea Pession ; MD ; PhD^b ; Emilio Franzoni ; MD^a
• 关键词：Vogt-Koyanagi-Harada disease ; children ; neurological manifestations ; panuveitis ; autoimmune
• 刊名：Pediatric Neurology
• 出版年：July 2014
• 年：2014
• 卷：51
• 期：1
• 页码：119-122
• 全文大小：633 K

文摘

Vogt-Koyanagi-Harada (VKH) disease is an autoimmune disorder characterized by ocular, auditory and neurological manifestations (headache, meningismus and/or aspeptic meningoencephalitis).

Patient

We describe a 12-year-old African boy with bilateral uveitis who presented with acute unilateral hearing loss and neurological symptoms such as left-sided dyskinesias, unsteady gait and throbbing headache. Brain magnetic resonance imaging showed ischemic lesions of the right basal ganglia in the territory of lenticulostriate and thalamic arteries. He improved after treatment with intravenous and oral steroids.

Conclusion

Cerebral ischemic episodes should be included in the possible neurological manifestations of VKH.