A comb-like branched β-d-glucan produced by a Cordyceps sinensis fungus and its protective effect against cyclophosphamide-induced immunosuppression in mice
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- 作者：Ting Hu ; Chenbo Jiang ; Qilin Huang ; hql@mail.hzau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; whuhql@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Fengyuan Sun
- 关键词：d-Glucose (PubChem CID ; 5793) ; d-Galactose (PubChem CID ; 6036) ; d-Mannose (PubChem CID ; 18950) ; d-Xylose (PubChem CID ; 135191) ; d-Arabinose (PubChem CID ; 229) ; d-Fucose (PubChem CID ; 840) ; d-Rhamnose (PubChem CID ; 5460029) ; Anthrone (PubChem CID ; 7018) ; Trifluoroacetic acid (PubChem CID ; 6422) ; Pyridine (PubChem CID ; 1049) ; Hydroxylamine hydrochloride (PubChem CID ; 443297) ; Sodium periodate (PubChem CID ; 23667635) ; Acetic anhydride (PubChem CID ; 7918) ; Chloroform (PubChem CID ; 6212) ; Ethylene gl
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 May 2016
- 年：2016
- 卷：142
- 期：Complete
- 页码：259-267
- 全文大小：887 K
文摘
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EPS was isolated from fermentation media of a Cordyceps sinensis fungus (Cs-HK1).
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EPS was nearly composed of d-glucose excluding a trace amount of d-mannose.
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EPS consisted of (1→3)-β-glucan backbone with single (1→6)-β-glucose as side chain.
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EPS showed a comb-like structure with (1→6)-β-glucose branch on every three glucoses.
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EPS could improve the levels of TNF-α and INF-γ to enhance immunomodulatory ability.