Structural elucidation, chain conformation and immuno-modulatory activity of glucogalactomannan from cultured Cordyceps sinensis fungus UM01
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- 作者：Kit-Leong Cheong1 ; Lan-Zhen Meng1 ; Xian-Qiang Chen1 ; Lan-Ying Wang ; Ding-Tao Wu ; Jing Zhao ; zhaojing.cpu@163.com" class="auth_mail" title="E-mail the corresponding author ; Shao-Ping Li
- 关键词：Cordyceps sinensis ; Polysaccharide ; Chain conformation ; Chemical structural ; Immuno-modulatory activity
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：25
- 期：Complete
- 页码：174-185
- 全文大小：1749 K
文摘
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UM01-S4 was purified from cultured mycelium of C. sinensis fungus UM01.
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The backbone of UM01-S4 mainly contained mannan units.
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UM01-S4 adapted sphere-like conformation in NaCl solution.
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UM01-S4 exhibited strong immuno-modulatory activity.
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MAPK and NF-κB signal transduction were the potential mechanism of UM01-S4.