Dysplastic erythroid precursors in the myelodysplastic syndromes and the acute myeloid leukemias: Is there biologic significance? (How should blasts be counted?)
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- 作者：John M. Bennetta ; john_bennett@urmc.rochester.edu" class="auth_mail" title="E-mail the corresponding author ; Heinz Tuechlerb ; Carlo Aulc ; Corinna Struppd ; Ulrich Germingd
- 关键词：Acute myeloid leukemias (AML) ; Myelodysplastic syndromes (MDS)
- 刊名：Leukemia Research
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：47
- 期：Complete
- 页码：63-69
- 全文大小：1682 K
文摘
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In a series of MDS patients 15.7% of cases have 50% or more erythroid precursors (EP).
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Some have used the 50% rule for classifying blasts to move cases to a higher grade MDS.
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The “50%” rule does not enhance the prognostic impact of the classifications on survival or time to transformation.".
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This method of classification is no longer recommended.