Delineating the dynamic uptake and toxicity of Ni and Co mixtures in Enchytraeus crypticus using a WHAM-FTOX approach
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Metal uptake in enchytraeids linearly correlated with metal binding to humic acid.

WHAM-FTOX well predicted Ni and Co toxicity at different exposure times.

Ni toxicity increased with time until 14 d, while Co toxicity remained constant.

Acute model parameters cannot be directly used to predict chronic metal toxicity.

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