0349 : Chronic heart failure and diabetes: two frequent companions in clinical practice
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文摘
The objectives of our study are to show prevalence of diabetics in heart failure population and to compare epidemiological profiles of diabetics and non diabetics.

Material and methods

we included 1613 patients, diabetics and non diabetics, admitted in united of heart failure in our center of Cardiology 2006 to 2015. All patients were evaluated clinically with monitoring of blood pressure (BP), 6 min walk test and electrocardiogram. Two-dimensional echocardiography and laboratory tests were performed in all patients. Coronarography was realised at 298 patients. The data are presented as numbers, percentages, and medians with interquartile range. The distribution of variables was compared between diabetics and non diabetics by chi2 test with confidence intervals.

Results

1613 patients were studied, the median age was 65 years (42-94 years) and 63% were men. 519 (32%) had diabetes. Diabetic patients were younger than non diabetics (56 years and 66 years). Stroke (23% and 18%) and myocardial infarction (37% and 27%) were more frequent and renal function was more affected in diabetics group. Atrial fibrillation was lower in diabetics group (7% and 17%). Ejection fraction of left ventricle was higher (48,5% and 35%) in diabetics group, but 51% of them had diastolic dysfunction with higher filling pressures. There weren’t differences in coronarography. Concerning treatment, 34% of diabetics arrive at maximal beta-blockers treatment (more than non diabetics 16%). Frequence of decompensation was more important in diabetics group.

Conclusions

So, frequence of diabetes in Moroccan heart failure population is higher. Significant differences exist in comorbidities, ventricular function, maximal beta-blockers treatment and frequence of decompessation between diabetics and non diabetics with chronic heart failure. These findings emphasize the importance of individualised management and need for more comprehensive recruitment of diabetics in clinical trials.

The author hereby declares no conflict of interest

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