Morphological and genetic heterogeneity in multifocal lung adenocarcinoma: The case of a never-smoker woman
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- 作者：Laura Bonannoa ; laura.bonanno@ioveneto.it" class="auth_mail" title="E-mail the corresponding author ; laura.bonanno@hotmail.it" class="auth_mail" title="E-mail the corresponding author ; Fiorella Calabreseb ; fiorella.calabrese@unipd.it" class="auth_mail" title="E-mail the corresponding author ; Giorgia Nardoc ; giorgia.nardo@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Daniele Calistrid ; daniele.calistri@irst.emr.it" class="auth_mail" title="E-mail the corresponding author ; Michela Tebaldid ; michela.tebaldi@irst.emr.it" class="auth_mail" title="E-mail the corresponding author ; Gianluca Tedaldid ; gianluca.tedaldi@irst.emr.it" class="auth_mail" title="E-mail the corresponding author ; Valentina Poloa ; e ; valentina.polo@ioveneto.it" class="auth_mail" title="E-mail the corresponding author ; Stefania Vuljanb ; stefvu@hotmail.it" class="auth_mail" title="E-mail the corresponding author ; Adolfo Favarettoa ; adolfo.favaretto@ioveneto.it" class="auth_mail" title="E-mail the corresponding author ; PierFranco Contea ; e ; pierfranco.conte@unipd.it" class="auth_mail" title="E-mail the corresponding author ; Alberto Amadoria ; e ; albido@unipd.it" class="auth_mail" title="E-mail the corresponding author ; Federico Reaf ; federico.rea@unipd.it" class="auth_mail" title="E-mail the corresponding author ; Stefano Indraccoloc ; stefano.indraccolo@unipd.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：NSCLCs ; non-small cell lung cancers ; NGS ; next generation sequencing ; CT ; computed tomography ; 18FDG-PET ; 18-Fluoro-d-glucose positron emission tomography ; PS ; performance status ; ECOG ; eastern cooperative oncology group
- 刊名：Lung Cancer
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：96
- 期：Complete
- 页码：52-55
- 全文大小：768 K
文摘
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Intra- and intertumor heterogeneity in patients with multiple lung adenocarcinomas.
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Molecular profile may distinguish synchronous from methacronous lung carcinomas.
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Molecular patterns may also identify subclonal genetic alterations in lung cancer.
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Molecular findings may affect the treatment choice and the clinical outcome.