Detoxification of polycyclic aromatic hydrocarbons (PAHs) in Arabidopsis thaliana involves a putative flavonol synthase
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Dioxygenase (DOX) At5g05600 is inducible by the PAH phenanthrene.

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At5g05600 loss-of-function plant mutant lines are tolerant to phenanthrene.

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DOX loss-of-function plant lines accumulate low levels of H2O2 under PAH exposure.

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Over-expressing At5g05600 in plants causes plants to be hypersensitive to PAH.

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Phenanthrene is chemically modified by recombinant AT5G05600 in vitro.

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