MSCs can be differentially isolated from maternal, middle and fetal segments of the human umbilical cord
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- 作者：Jezamine Lim1 ; Zainul Rashid Mohamad Razi2 ; Jiaxian Law1 ; Azmawati Mohammed Nawi3 ; Ruszymah Binti Haji Idrus1 ; 4 ; Min Hwei Ng1 ; angelaster3@gmail.com" class="auth_mail" title="E-mail the corresponding author ; angela@ppukm.ukm.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：regenerative medicine ; stromal cells ; tissue engineering ; umbilical cord ; Wharton's jelly
- 刊名：Cytotherapy
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：18
- 期：12
- 页码：1493-1502
- 全文大小：2213 K
文摘
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We compared MSCs isolated from 3 anatomical segments of umbilical cord (maternal, middle and foetal).
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Results showed that the cells exhibited different growth rate, expression of embryonic markers and multilineage differentiation potential.
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The selection of umbilical cord segments for cell isolation is important to harvest MSCs with best therapeutic potential.