Harnessing the power of cell transplantation to target respiratory dysfunction following spinal cord injury
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- 作者：Brittany A. Charsar ; Mark W. Urban ; Angelo C. Lepore ; angelo.lepore@jefferson.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：BDNF ; brain-derived neurotrophic factor ; BMNC ; bone marrow nucleated cell ; C2 ; 3 ; 4 ; etc. ; cervical level 2 ; 3 ; 4 ; etc. ; ChABC ; chondroitinase ABC ; CMAP ; compound muscle action potential ; CNS ; central nervous system ; CPP ; crossed phrenic phenomenon ; CSPG ; chondroitin sulfate proteoglycan ; EMG ; electromyography ; ES cells ; embryonic stem cells ; FSC ; fetal spinal cord ; GAG ; glycosaminoglycan ; GLT1 ; glutamate transporter 1 ; GRP ; glial-restricted precursor ; iPS cell ; induced Pluripotent Stem cell ; MB
- 刊名：Experimental Neurology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：287
- 期：part_P2
- 页码：268-275
- 全文大小：509 K
文摘
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Cell transplantation is a promising therapeutic strategy for SCI.
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Respiratory dysfunction plays a critical role in patient outcome following SCI.
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Transplant-based targeting of respiratory compromise has not been extensively explored.
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A small number of studies to date have shown the potential power of such an approach.