Kidney function in sugarcane cutters in Nicaragua - A longitudinal study of workers at risk of Mesoamerican nephropathy
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- 作者：Catharina Wesselinga ; inekewesseling@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Aurora Aragó ; nb ; auroraragon@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Marvin Gonzá ; lezb ; c ; marvin99_00@yahoo.es" class="auth_mail" title="E-mail the corresponding author ; Ilana Weissd ; ilana@laislafoundation.org" class="auth_mail" title="E-mail the corresponding author ; Jason Glaserd ; jason@laislafoundation.org" class="auth_mail" title="E-mail the corresponding author ; Norma A. Bobadillae ; f ; nab@biomedicas.unam.mx" class="auth_mail" title="E-mail the corresponding author ; Carlos Roncal-Jimé ; nezg ; tamara.harra@ucdenver.edu" class="auth_mail" title="E-mail the corresponding author ; Carlos.Roncal@ucdenver.edu" class="auth_mail" title="E-mail the corresponding author ; Ricardo Correa-Rottere ; correarotter@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Richard J. Johnsong ; Richard.Johnson@ucdenver.edu" class="auth_mail" title="E-mail the corresponding author ; Lars Barregardh ; lars.barregard@amm.gu.se" class="auth_mail" title="E-mail the corresponding author
- 关键词：BMI ; Body mass index ; CKD ; Chronic kidney disease ; eGFR ; estimated glomerular filtration rate ; KIM-1 ; Kidney injury molecule 1 ; MeN ; Mesoamerican nephropathy ; NGAL ; neutrophil gelatinase-associated lipocalin ; Hsp72 ; Heat shock protein 72 kD ; NSAIDS ; Non-steroid anti-inflammatory drugs ; RAAS ; renin-angiotensin-aldosterone system
- 刊名：Environmental Research
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：147
- 期：Complete
- 页码：125-132
- 全文大小：335 K
文摘
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We examined sugarcane cutters at start of harvest and 9 weeks later.
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Pre-shift renal function decreased substantially after 9 weeks of harvest work.
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Estimated glomerular filtration rate decreased by 10 mL/min.
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Serum urea N (BUN) and urinary NGAL also increased substantially.
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Repeated dehydration is a likely cause of long-term decrease in renal function.