Vitexin-2-O-xyloside was purified from Beta vulgaris cicla seeds.
Betalains were purified from red beet root by anionic exchange chromatography.
Betalains increase vitexin-2-O-xyloside cytotoxicity in CaCo-2 colon cancer cells.
The cytotoxic effect is mediated by activation of an intrinsic apoptotic pathway.