Occurrence of fibronectin-fibrin complexes in plasma of patients with multimorbidity due to the inflamm-aging phenomenon
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- 作者：Małgorzata Pupeka ; malgorzata.pupek@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author ; Robert Pawłowiczb ; robert.pawlowicz@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author ; Karolina Lindnerb ; karolina.lindner@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author ; Dorota Krzyżanowska-Gołąba ; dorota.krzyzanowska-golab@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author ; Anna Lemańska-Pereka ; anna.lemanska-perek@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author ; Bernard Panaszekb ; bernard.panaszek@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author ; Iwona Kątnik-Prastowskaa ; maria.katnik-prastowska@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Fibronectin ; EDA-fibronectin ; FN&ndash ; fibrin complexes ; FN agarose-immunoblotting ; C-reactive protein ; Multimorbidity
- 刊名：Experimental Gerontology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：19-28
- 全文大小：827 K
文摘
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Plasma FN–fibrin complexes accompanied chronic diseases with low-grade inflammation.
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The decrease of plasma FN monomer was related to multimorbidity.
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The decrease of FN and of EDA-FN concentrations was associated with multimorbidity.
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The increase of FN and decrease of EDA-FN with aging were observed.
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The plasma FN molecular status was associated with micro-inflammation and micro-coagulation.