Spectroscopic, structural and in vitro cytotoxicity evaluation of luminescent, lanthanide doped core@shell nanomaterials GdVO₄:Eu³⁺5%@SiO₂@NH₂

详细信息    查看全文

• 作者：Agata Szczeszak^a ; ^{agata_is@amu.edu.pl" class="auth_mail" title="E-mail the corresponding author} ; Anna Ekner-Grzyb^b ; ^{anna.ekner@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Marcin Runowski^a ; ^{runowski@amu.edu.pl" class="auth_mail" title="E-mail the corresponding author} ; Kosma Szutkowski^c ; ^{kosma.szutkowski@outlook.com" class="auth_mail" title="E-mail the corresponding author} ; Lucyna Mró ; wczyńska^d ; ^{lumro@amu.edu.pl" class="auth_mail" title="E-mail the corresponding author} ; Zuzanna Kaźmierczak^e ; ^{zuzanna.kazmierczak@iitd.pan.wroc.pl" class="auth_mail" title="E-mail the corresponding author} ; Tomasz Grzyb^a ; ^{tgrzyb@amu.edu.pl" class="auth_mail" title="E-mail the corresponding author} ; Krystyna Dąbrowska^e ; ^{dabrok@iitd.pan.wroc.pl" class="auth_mail" title="E-mail the corresponding author} ; Michael Giersig^f ; ^{giersig@physik.fu-berlin.de" class="auth_mail" title="E-mail the corresponding author} ; Stefan Lis^a ; ^{blis@amu.edu.pl" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Nanomaterials ; Lanthanide ions ; Luminescence ; Orthovanadates ; Surface modification ; Cytotoxicity ; Biocompability
• 刊名：Journal of Colloid and Interface Science
• 出版年：2016
• 出版时间：1 November 2016
• 年：2016
• 卷：481
• 期：Complete
• 页码：245-255
• 全文大小：5439 K

文摘

The luminescent GdVO₄:Eu³⁺5%@SiO₂@NH₂ core@shell nanomaterials were obtained via co-precipitation method, followed by hydrolysis and co-condensation of silane derivatives: tetraethyl orthosilicate and 3-aminopropyltriethoxysilane. Their effect on human erythrocytes sedimentation and on proliferation of human lung microvascular endothelial cells was examined and discussed. The luminescent nanoparticles were synthesized in the presence of polyacrylic acid or glycerin in order to minimalize the agglomeration and excessive growth of nanostructures. Surface coating with amine functionalized silica shell improved their biocompatibility, facilitated further organic conjugation and protected the internal core. Magnetic measurements revealed an enhanced T₁-relaxivity for the synthesized GdVO₄:Eu³⁺5% nanostructures. Structure, morphology and average grain size of the obtained nanomaterials were determined by X-ray diffraction, transmission electron microscopy and dynamic light scattering analysis. The qualitative elemental composition of the nanomaterials was established using energy-dispersive X-ray spectroscopy. The spectroscopic characteristic of red emitting core@shell nanophosphors was completed by measuring luminescence spectra and decays. The emission spectra revealed characteristic bands of Eu³⁺ ions related to the transitions ⁵D₀-⁷F_0,1,2,3,4 and ⁵D₁-⁷F₁. The luminescence lifetimes consisted of two components, associated with the presence of Eu³⁺ ions located at the surface of the crystallites and in the bulk.