A water-soluble and biocompatible polymeric nanolabel based on naphthalimide grafted poly(acrylic acid) for the two-photon fluorescence imaging of living cells and C. elegans
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- 作者：Shucai Lianga ; chirolab@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yongmei Liua ; Ting Fub ; Fan Yanga ; Xiaohui Chenb ; Guoping Yanb ; guopyan2006@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Polymeric nanoparticle ; Two-photon fluorescence imaging ; Living cell ; C. elegans ; Poly(acrylic acid) ; Naphthalimide
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 December 2016
- 年：2016
- 卷：148
- 期：Complete
- 页码：293-298
- 全文大小：1439 K
文摘
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A new polymeric nanolabel with two-photon activity was developed.
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The nanolabel possessed good water-dispersity, pH stability and high photostability.
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Biocompatibility was evaluated by the cytotoxicity and C. elegans feeding behavior.
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Two-photon fluorescence imaging in cells and C. elegans was successfully achieved.
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The nanolabel has the potential to be used in multifunctional probes.