Comparative proteomic analysis of Litopenaeus vannamei gills after vaccination with two WSSV structural proteins
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- 作者：Li-Hao Chena ; 1 ; Shi-Wei Lina ; Kuan-Fu Liub ; Chin-I Changc ; Jinn-Rong Hseud ; Jyh-Ming Tsaia ; jmtsai@webmail.nkmu.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Proteomic analysis ; White spot syndrome virus (WSSV) ; Shrimp ; Vaccine ; Invertebrate immunity
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：49
- 期：Complete
- 页码：306-314
- 全文大小：882 K
文摘
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Shrimp were injected with two viral proteins, but only rVP28 triggered resistance against WSSV.
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20 differentially expressed proteins were identified by 2-DE/MS analysis after vaccination.
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Many proteins with their expression levels also participate in the shrimp's response during WSSV infection.
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Chymotrypsin and trypsin were significantly increased in shrimp of both vaccinated groups compared to PBS controls.
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The up-regulated proteins exclusively in rVP28-vaccinated shrimp include calreticulin, HSP70, ubiquitin and others.