Exploration of reasons for variation of response of DCM patients to therapy by IA/IgG vary.
Myocardial proteome profiling of responders and non-responders was performed.
Patient subgroups differ in energy and lipid metabolism, immune system and cardioprotection.
Most prominent differences were found for proteins S100-A8, perilipin-4, and kininogen-1.
Biomarker potential of these three proteins was evaluated.