Exploring the venom of the forest cobra snake: Toxicovenomics and antivenom profiling of Naja melanoleuca
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- 作者：Line P. Lauridsena ; Andreas H. Laustsena ; b ; Bruno Lomontec ; José ; Marí ; a Gutié ; rrezc ; jose.gutierrez@ucr.ac.cr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Naja melanoleuca ; Forest cobra ; Snake venom ; Proteomics ; Toxicovenomics ; Antivenoms
- 刊名：Journal of Proteomics
- 出版年：2017
- 出版时间：6 January 2017
- 年：2017
- 卷：150
- 期：Complete
- 页码：98-108
- 全文大小：928 K
文摘
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The proteome of the venom of the forest cobra, Naja melanoleuca, was studied.
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The main venom components are α-neurotoxins of the three finger family and phospholipases A2.
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The RP-HPLC fractions inducing lethality correspond to α-neurotoxins.
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Antivenoms from South Africa and India immunoreact with all venom fractions.