Employing an MHC-matched, minor transplantation antigen–mismatched allogeneic model of matched unrelated donor, we developed clinical scoring criterion identifying degrees of ocular pathology at both the ocular surface and adnexa

The association of these clinical changes with the development of immune responses around the ocular adnexa is monitored in real time

We report, for the first time, that these clinical and immune responses occur not only on the ocular surface, but they also heavily involve the lid margin region

Studies facilitate a standardized analysis of the immunologic and pathologic findings in the eye that occurs in animal models of ocular graft-versus-host disease