A cellular and molecular mosaic establishes growth and differentiation states for cranial sensory neurons
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- 作者：Beverly A. Karpinskia ; b ; d ; anabko@gwu.edu" class="auth_mail" title="E-mail the corresponding author ; Corey A. Bryana ; d ; cbryan98@email.gwu.edu" class="auth_mail" title="E-mail the corresponding author ; Elizabeth M. Paronetta ; d ; eparonett@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jennifer L. Bakerc ; jennifer.l.baker.7@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Alejandra Fernandeza ; d ; alefdz@gwu.edu" class="auth_mail" title="E-mail the corresponding author ; Anelia Horvatha ; d ; horvatha@email.gwu.edu" class="auth_mail" title="E-mail the corresponding author ; Thomas M. Maynarda ; d ; maynard@gwu.edu" class="auth_mail" title="E-mail the corresponding author ; Sally A. Moodyb ; d ; samoody@gwu.edu" class="auth_mail" title="E-mail the corresponding author ; Anthony-S. LaMantiaa ; d ; lamantia@gwu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cranial sensory neurons ; Placodes ; Neural crest ; Six1 ; Wnt1 ; Cre ; Retinoic acid ; Fgf ; Olfactory ; Otic ; Cranial sensory ganglia
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：415
- 期：2
- 页码：228-241
- 全文大小：19118 K
文摘
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Cranial sensory neuron lineage or transcription factors do not follow A–P gradient.
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Disrupting Fgfs or RA signaling does alter these in an A–P gradient.
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Diminished Fgf enhances anterior cell death; diminished RA enhances it posteriorly.
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Diminished Fgf disrupts anterior nerves; diminished RA affects posterior ones.