Functional Neuronavigation-Guided Transparieto-Occipital Cortical Resection of Meningiomas in Trigone of Lateral Ventricle

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• 作者：Guo-chen Sun¹ ; ^&lowast ; ; Xiao-lei Chen¹ ; ^&lowast ; ; Xin-guang Yu¹ ; Meng Zhang¹ ; Gang Liu² ; Bao-ke Hou³ ; Xiao-dong Ma¹ ; ^{sjwk8082@126.com" class="auth_mail" title="E-mail the corresponding author} ; ^{sjwk301@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Functional neuronavigation ; Image-guided surgery ; Meningioma ; Optic radiation
• 刊名：World Neurosurgery
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：84
• 期：3
• 页码：756-765
• 全文大小：3063 K

文摘

This study investigated whether functional neuronavigation can be used to remove lesions in the lateral ventricle while preserving patients' neurologic functionality.

Methods

A total of 60 patients with lateral ventricular meningiomas were divided into study and control groups (n = 30 each). Diffusion tensor and blood oxygenation level–dependent functional magnetic resonance imaging were used for fiber tracking and eloquent cortex localization, respectively, in the study group. The surgical approach was based on coregistered data sets from 3-D lesion and brain structure reconstructions. Patients in the control group underwent anatomic neuronavigation-guided surgery. The patients' demographics, degree of resection, visual field, language score, movement, preoperative and postoperative Karnofsky Performance Status (KPS) scores, and surgical complications were recorded.

Results

Tumors were completely removed in both groups. Patients in the study group had a higher rate of visual field preservation than controls (P = 0.01). The two groups had similar motor and language functions after surgery, except that fewer cases of transient aphasia were observed in the former (P < 0.05). KPS scores for the study and control groups were 80 (70–80) and 70 (60–70), respectively (P < 0.01), at 2 weeks and 90 (80–100) and 85 (70–90), respectively (P = 0.022), at 3 months after surgery.

Conclusions

Functional neuronavigation preserved neurologic functionality and was especially beneficial for protecting optical functionality and for the rapid recovery of patients.