Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage
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- 作者：Yung-Ting Changa ; poppiiyy@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Chiung-Yao Huangb ; betty8575@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author ; Kun-Tzu Lic ; sherry30126@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author ; Ruei-Nian Lic ; runili@kmu.edu.tw" class="auth_mail" title="E-mail the corresponding author ; Chih-Chuang Liawa ; b ; ccliaw@mail.nsysu.edu.tw" class="auth_mail" title="E-mail the corresponding author ; Shih-Hsiung Wua ; d ; shwu@gate.sinica.edu.tw" class="auth_mail" title="E-mail the corresponding author ; Jing-Ru Liuc ; clumyfish2006@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jyh-Horng Sheua ; b ; f ; sheu@mail.nsysu.edu.tw" class="auth_mail" title="E-mail the corresponding author ; Hsueh-Wei Changc ; e ; g ; h ; changhw@kmu.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Soft corals ; Sinuleptolide ; Oral cancer ; Apoptosis ; DNA damage ; Mitochondrial membrane potential
- 刊名：Archives of Oral Biology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：66
- 期：Complete
- 页码：147-154
- 全文大小：1596 K
文摘
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In this study we examine the antioral cancer effect of sinuleptolide.
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We examine changes in cell growth, apoptosis, DNA damage, oxidative stress.
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We conclude that sinuleptolide has potential as a chemotherapeutic agent against oral cancer.