Prognostic value of imbalanced interhemispheric functional coordination in early therapeutic efficacy in major depressive disorder
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The non-responding depression showed altered interhemispheric coordination.

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The abnormal VMHC was related to the severity of depression.

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The VMHC changes can effectively identify patients with poorer treatment response.

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The interhemispheric synchrony may sever as a predictor of early response in MDD.

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