Regenerated cellulose/wool blend enhanced biomimetic hydroxyapatite mineralization
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- 作者：Ahmed Salama ; Ahmed_nigm78@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Mohamed El-Sakhawy
- 关键词：Cellulose ; Wool ; Ionic liquid ; Calcium phosphate ; Mineralization
- 刊名：International Journal of Biological Macromolecules
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：92
- 期：Complete
- 页码：920-925
- 全文大小：2140 K
文摘
The current article investigates the effect of bioactive cellulose/wool blend on calcium phosphate biomimetic mineralization. Regenerated cellulose/wool blend was prepared by dissolution-regeneration of neat cellulose and natural wool in 1-butyl-3-methyl imidazolium chloride [Bmim][Cl], as a solvent for the two polymers. Crystalline hydroxyapatite nanofibers with a uniform size, shape and dimension were formed after immersing the bioactive blend in simulated body fluid. The cytotoxicity of cellulose/wool/hydroxyapatite was studied using animal fibroblast baby hamster kidney cells (BHK-21) and the result displayed good cytocompatability. This research work presents a green processing method for the development of novel cellulose/wool/hydroxyapatite hybrid materials for tissue engineering applications.