Wilson and early-onset Parkinson diseases are uneasy to distinguish in atypical cases.
We compared transcranial sonography-MRI fusion imaging in these disorders.
Lentiform nucleus hyperechogenicity has high sensitivity/specificity for their differentiation.
Lentiform nucleus hyperechogenicity is only partly related to MRI T2 hyperintensity.
Transcranial sonography is a helpful screening method complementary to MRI.