α-syn accumulates in the mesencephalon, striatum and frontal cortex of m/m rats.
SNpc DAergic neurons from m/m rats show normal functional activity.
The number of SNpc DAergic neurons from m/m rats is 9% reduced.
Dopamine and glutamate release in the striatum from m/m rats is impaired.
Loss of striatal DAT- and VGluT1-expressing terminals occurs in m/m rats.