Genotoxicity and oxidative stress induced by the fungicide azoxystrobin in zebrafish (Danio rerio) livers
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- 作者：Yingnan Han hyn_call@163.com" class="auth_mail" title="E-mail the corresponding author ; Tong Liu liutongdsg@126.com" class="auth_mail" title="E-mail the corresponding author ; Jinhua Wang ; wjh@sdau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jun Wang jwang@sdau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Cheng Zhang ymzhangcheng@163.com" class="auth_mail" title="E-mail the corresponding author ; Lusheng Zhu ; lushzhu@vip.163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ROS ; SOD ; CAT ; GST ; LPO ; Comet assay
- 刊名：Pesticide Biochemistry and Physiology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：133
- 期：Complete
- 页码：13-19
- 全文大小：1057 K
文摘
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Azoxystrobin induced oxidative stress and genotoxicity in zebrafish livers.
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ROS was generated in excess.
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SOD was inhibited, CAT and GST were stimulated at most azoxystrobin treatments.
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Lipid peroxidation increased as a consequence of oxidative stress.
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The excess ROS was one of the causes for the DNA damage.