Calpain inhibitor attenuates ER stress-induced apoptosis in injured spinal cord after bone mesenchymal stem cells transplantation
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- 作者：Chao Wanga ; w78084897@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Dongling Shib ; 21318209@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xinghui Songc ; songxh@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yingying Chenb ; bchenyy@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Linlin Wangb ; wanglinlin@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiaoming Zhanga ; zxm@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mesenchymal stem cell ; MDL28170 ; Spinal cord injury ; ER stress ; Apoptosis
- 刊名：Neurochemistry International
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：97
- 期：Complete
- 页码：15-25
- 全文大小：2987 K
文摘
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MDL28170 protected BMSCs survival after transplantation to the injured spinal cord.
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MDL28170 rescued BMSCs by inhibiting the ER stress-induced apoptosis.
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We propose a new strategie for using MDL28170 with BMSCs in the therapy of injured spinal cord.