Complications and oncologic outcomes following elective neck dissection with salvage laryngectomy for the N0 neck

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• 作者：Monika E. Freiser ; MD ; MPH^a ; ¹ ; ^{freiserme@upmc.edu" class="auth_mail" title="E-mail the corresponding author} ; Rosemary B. Ojo ; MD^a ; ² ; ^{rojo@earsinus.com" class="auth_mail" title="E-mail the corresponding author} ; Kaming Lo ; MPH^b ; ^{Klo@biostat.med.miami.edu" class="auth_mail" title="E-mail the corresponding author} ; Sandra Saint-Victor ; MD^a ; ^{Sandra.saintvictor@jhsmiami.org" class="auth_mail" title="E-mail the corresponding author} ; Craig Bollig ; MD^a ; ³ ; ^{bolligc@health.missouri.edu" class="auth_mail" title="E-mail the corresponding author} ; Chetan S. Nayak ; MD^a ; ^{CNayak@med.miami.edu" class="auth_mail" title="E-mail the corresponding author} ; Zoukaa B. Sargi ; MD ; MPH^a ; ^{zsargi@med.miami.edu" class="auth_mail" title="E-mail the corresponding author}
• 刊名：American Journal of Otolaryngology
• 出版年：2016
• 出版时间：May-June 2016
• 年：2016
• 卷：37
• 期：3
• 页码：186-194
• 全文大小：464 K

文摘

To investigate the difference in survival and complication outcomes between patients with a clinically and radiologically N0 neck who received an elective neck dissection at the time of salvage total laryngectomy compared to those who had salvage total laryngectomy alone.

Materials and methods

A retrospective chart review was performed on 125 salvage total laryngectomy patients who were clinically and radiologically N0 preoperatively. Performance of an elective neck dissection and other factors were tested for associations with various postoperative complications, disease-free survival, and overall survival.

Results

Ninety-eight patients underwent elective neck dissection, of which ten had positive nodal pathology. Elective neck dissection was not significantly associated with complications or survival outcomes. Positive nodal disease was associated with worse disease-free and overall survival on multivariate analysis.

Conclusions

In patients with clinically and radiologically N0 necks undergoing salvage total laryngectomy, an elective neck dissection can provide prognostic information but does not appear to be significantly associated with increased complications or improved survival.