ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure
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- 作者：Saumya Jain1 ; 4 ; Joshua R. Wheeler1 ; 4 ; Robert W. Walters1 ; Anurag Agrawal2 ; Anthony Barsic2 ; Roy Parker1 ; 3 ; roy.parker@colorado.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell
- 出版年：2016
- 出版时间：28 January 2016
- 年：2016
- 卷：164
- 期：3
- 页码：487-498
- 全文大小：3234 K
文摘
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Stress granules are composed of stable cores surrounded by a phase-separated shell
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Purification of cores identified new members of the stress granule proteome
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Granule assembly and dynamics are modulated by ATP
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CCT, RVB, and MCM ATPases regulate distinct steps in granule assembly/disassembly