Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development
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- 作者：Jessica Endig1 ; 13 ; Laura Elisa Buitrago-Molina1 ; 13 ; Silke Marhenke1 ; 13 ; Florian Reisinger2 ; Anna Saborowski1 ; Jutta Schü ; tt3 ; Florian Limbourg4 ; Christian Kö ; necke5 ; Alina Schreder5 ; Alina Michael1 ; Ana Clara Misslitz1 ; Marc Eammonn Healy6 ; Robert Geffers7 ; Thomas Clavel8 ; Dirk Haller8 ; Kristian Unger9 ; Milton Finegold10 ; Achim Weber6 ; Michael P. Manns1 ; Thomas Longerich11 ; Mathias Heikenwä ; lder3 ; 12 ; Arndt Vogel1 ; vogel.arndt@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cancer Cell
- 出版年：2016
- 出版时间：8 August 2016
- 年：2016
- 卷：30
- 期：2
- 页码：308-323
- 全文大小：8444 K
文摘
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Flares of liver injury accelerate hepatocarcinogenesis
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The adaptive immune system has a dual role in chronic liver injury
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The immune system is not required for liver regeneration during chronic injury
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CD8+ T cells and LTβR contribute to hepatocarcinogenesis in chronic injury