Investigation of cerebral microbleeds in multiple sclerosis as a potential marker of blood-brain barrier dysfunction
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- 作者：Philipp Eisele eisele@neuro.ma.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author ; Angelika Alonso alonso@neuro.ma.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author ; Martin Griebe griebe@neuro.ma.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author ; Kristina Szabo szabo@neuro.ma.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author ; Michael G. Hennerici hennerici@neuro.ma.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author ; Achim Gass ; achim.gass@medma.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：BBB ; blood-brain-barrier ; CMB ; cerebral microbleeds ; EDSS ; Expanded Disability Status Scale ; MRI ; magnetic resonance imaging ; MS ; multiple sclerosis ; SVD ; small vessel disease ; T2*w ; T2*-weighted MRI ; WML ; white matter lesions
- 刊名：Multiple Sclerosis and Related Disorders
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：7
- 期：Complete
- 页码：61-64
- 全文大小：567 K
文摘
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MS represents a disease with a high prevalence of a blood-brain-barrier disturbance.
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Using gradient-echo T2* MRI we found no cerebral microbleeds in MS patients.
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Cerebral microbleeds do not appear to be useful vascular/inflammatory markers in MS.