Challenges in structural approaches to cell modeling
详细信息 查看全文
- 作者：Wonpil Im1 ; wonpil@ku.edu" class="auth_mail" title="E-mail the corresponding author ; Jie Liang2 ; jliang@uic.edu" class="auth_mail" title="E-mail the corresponding author ; Arthur Olson3 ; olson@scripps.edu" class="auth_mail" title="E-mail the corresponding author ; Huan-Xiang Zhou4 ; hzhou4@fsu.edu" class="auth_mail" title="E-mail the corresponding author ; Sandor Vajda5 ; vajda@bu.edu" class="auth_mail" title="E-mail the corresponding author ; Ilya A. Vakser1 ; vakser@ku.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：modeling of biological mesoscale ; protein interactions ; macromolecular crowding ; cellular membranes ; chromosome modeling
- 刊名：Journal of Molecular Biology
- 出版年：2016
- 出版时间：31 July 2016
- 年：2016
- 卷：428
- 期：15
- 页码：2943-2964
- 全文大小：2605 K
文摘
- class="listitem" id="list_l0005">
- class="label">•
Structural characterization is key to our understanding of biomolecular mechanisms
- class="label">•
Modeling of biomolecules and their interactions has been rapidly progressing
- class="label">•
The current focus is shifting toward larger systems, up to the level of a cell
- class="label">•
The review describes structural approaches to cell modeling and future development