Reengineered graft copolymers as a potential alternative for the bone tissue engineering application by inducing osteogenic markers expression and biocompatibility
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- 作者：Muthukumar Thangavelua ; c ; auromuthu@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Raghavan R. Narasimhaa ; Aravinthan Adithanc ; Chandrasekaran A.b ; Kim Jong-Hoonc ; jhkim1@jbnu.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Sastry Thotapalli Parvathaleswaraa ; sastrytp@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bone ; Osteonectin ; Osteopontin ; Osteocalcin ; Collagen type I
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：143
- 期：Complete
- 页码：15-26
- 全文大小：6772 K
文摘
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BCP was graft copolymerized with PGMA with and without incorporation of DBM.
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Porous scaffolds are biocompatible, supporting growth, maturation of MG63 cells.
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Increased early and late osteogenic markers.
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Capable of supporting the in vitro growth and maturation of osteoblast-like cells.
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In vivo and in vitro results confirming osteoinductivity of scaffold.