Enriched rehabilitation promotes motor recovery in rats exposed to neonatal hypoxia-ischemia
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- 作者：Clarissa Pedrini Schucha ; b ; Matthew Strider Jeffersa ; h ; Sabina Antonescua ; h ; Carine Nguemenia ; h ; Mariana Gomez-Smitha ; h ; Lenir Orlandi Pereirab ; Cindi M. Morsheadc ; d ; e ; Dale Corbetta ; f ; g ; h ; dcorbett@uottawa.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：HI ; hypoxia-ischemia ; ER ; enriched rehabilitation ; CsA ; cyclosporine A ; PND ; postnatal day
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 May 2016
- 年：2016
- 卷：304
- 期：Complete
- 页码：42-50
- 全文大小：1711 K
文摘
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A combination therapy of cyclosporine A and enriched rehabilitation is evaluated.
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Enriched rehabilitation promotes motor recovery.
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Sensitive behavioural tests can detect early impairments in hypoxic-ischemic rats.
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CsA given 2 weeks after HI is not therapeutically efficacious.