Tentative identification of the composition of Agaricus bisporus aqueous enzymatic extracts with antiviral activity against HCV: A study by liquid chromatography-tandem mass spectrometry in high resolution mode
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- 作者：Marí ; a del Mar Delgado-Povedanoa ; b ; c ; Veró ; nica Sá ; nchez de Medinaa ; b ; c ; Juan Bautistad ; jdbaut@us.es" class="auth_mail" title="E-mail the corresponding author ; Feliciano Priego-Capotea ; b ; c ; Marí ; a Dolores Luque de Castroa ; b ; c ; qa1lucam@uco.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mushroom ; Agaricus bisporus ; Aqueous enzymatic extracts ; Liquid chromatography&ndash ; tandem mass spectrometry ; Antiviral activity ; HCV
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：24
- 期：Complete
- 页码：403-419
- 全文大小：1612 K
文摘
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Sequential fractionation of AbAEE with anti-VCH protease NS3 activity.
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Use of different polarity extractants for efficient AbAEE fractionation.
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123 compounds were tentatively identified by MS/MS information.
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55 out of the 123 compounds tentatively identified had not been identified before.
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LC–QTOF MS/MS was confirmed as strategy for overall metabolome coverage of AbAEE.