Development of a method for enhancing metabolomics coverage of human sweat by gas chromatography-mass spectrometry in high resolution mode
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- 作者：M.M. Delgado-Povedanoa ; b ; c ; M. Calderó ; n-Santiagoa ; b ; c ; b42casam@uco.es" class="auth_mail" title="E-mail the corresponding author ; F. Priego-Capotea ; b ; c ; M.D. Luque de Castroa ; b ; c ; qa1lucam@uco.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Metabolomics ; Global profiling ; Human sweat ; Gas chromatography&ndash ; mass spectrometry ; Human sweat metabolome ; Sample preparation
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：28 January 2016
- 年：2016
- 卷：905
- 期：Complete
- 页码：115-125
- 全文大小：614 K
文摘
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Methyoxiamination and silylation after deproteinization for a snapshot of sweat metabolome.
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GC–TOF/MS, an excellent strategy to analyze sweat in terms of metabolome coverage.
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Comparison of the GC–TOF/MS study with previous studies using NMR or LC–MS.
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Sixty-six compounds were tentatively identified by the obtained MS information.