Emerging Entities in Renal Neoplasia

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• 作者：Rohit Mehra ; MD^a ; Steven C. Smith ; MD^b ; Mukul Divatia ; MD^b ; Mahul B. Amin ; MD^b ; ^{mahul.amin@cshs.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Renal cell carcinoma ; Tubulocystic ; Translocation ; Acquired cystic disease ; Thyroid-like follicular ; Hereditary ; Leiomyomatosis
• 刊名：Surgical Pathology Clinics
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：8
• 期：4
• 页码：623-656
• 全文大小：22564 K

文摘

This article reviews emerging entities in renal epithelial neoplasia, including tubulocystic carcinoma, clear-cell–papillary renal cell carcinoma (RCC), thyroid-like follicular RCC, ALK-related RCC, translocation RCC, acquired cystic disease–related RCC, succinate dehydrogenase–deficient RCC, and hereditary leiomyomatosis-RCC syndrome–associated RCC. Many of these rarer subtypes of RCC were recently studied in more depth and are included in the upcoming version of the World Health Organization classification of tumors. Emphasis is placed on common gross and morphologic features, differential diagnoses, use of ancillary studies for making accurate diagnoses, molecular alterations, and predicted biologic behavior based on previous studies.