Stunting correlates with high salivary and serum antibody levels after 13-valent pneumococcal conjugate vaccination of Venezuelan Amerindian children
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- 作者：Lilly M. Verhagena ; b ; c ; L.M.Verhagen-4@umcutrecht.nl" class="auth_mail" title="E-mail the corresponding author ; Meyke Hermsend ; Ismar Rivera-Oliveroa ; Marí ; a Carolina Siscoa ; Elena Pinellie ; Peter W.M. Hermansb ; 1 ; Guy A.M. Berberse ; Jacobus H. de Waarda ; Marien I. de Jongeb
- 关键词：13-Valent pneumococcal conjugate vaccination ; Indigenous children ; Chronic malnutrition ; Saliva ; Venezuela
- 刊名：Vaccine
- 出版年：2016
- 出版时间：29 April 2016
- 年：2016
- 卷：34
- 期：20
- 页码：2312-2320
- 全文大小：1599 K
文摘
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In Venezuelan children, PCV13 salivary and serum antibody levels correlated well.
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Saliva may be used as a read-out for PCV13 vaccine response.
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Stunted children had higher specific serum and salivary PCV13 antibody levels.
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More studies addressing the effect of malnutrition on vaccine induced responses are needed.