4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer
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- 作者：Tommaso De Marchia ; h ; t.demarchi@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Ning Qing Liua ; 1 ; n.liu@ncmls.ru.nl" class="auth_mail" title="E-mail the corresponding author ; Cristoph Stinglb ; c.stingl@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Mieke A. Timmermansa ; a.timmermans@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Marcel Smida ; m.smid@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Maxime P. Looka ; m.look@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Mila Tjoaa ; milatjoa@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Rene B.H. Braakmana ; h ; r.braakman@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Mark Opdamc ; m.opdam@nki.nl" class="auth_mail" title="E-mail the corresponding author ; Sabine C. Linnc ; s.linn@nki.nl" class="auth_mail" title="E-mail the corresponding author ; Fred C.G.J. Sweepd ; f.sweep@labgk.umcn.nl" class="auth_mail" title="E-mail the corresponding author ; Paul N. Spane ; P.Span@rther.umcn.nl" class="auth_mail" title="E-mail the corresponding author ; Mike Kliffenf ; KliffenM@maasstadziekenhuis.nl" class="auth_mail" title="E-mail the corresponding author ; Theo M. Luiderb ; t.luider@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; John A. Foekensa ; j.foekens@erasmsumc.nl" class="auth_mail" title="E-mail the corresponding author ; John W.M. Martensa ; g ; j.martens@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Arzu Umara ; a.umar@erasmsumc.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Breast cancer ; Proteomics ; Tamoxifen resistance ; Biomarker ; Mass spectrometry
- 刊名：Molecular Oncology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：10
- 期：1
- 页码：24-39
- 全文大小：2317 K
文摘
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Analysis of hormonal naïve cohorts of patients with recurrent breast cancer.
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Laser microdissection based enrichment of epithelial breast tumors.
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High resolution mass spectrometric analysis of epithelial breast tumors.
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Development and validation of a protein signature predicting tamoxifen outcome.
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Validation by immunohistochemistry in independent cohort.