Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling
详细信息 查看全文
- 作者：Jung-Chien Chenga ; Hsun-Ming Changa ; Pang-Pin Liua ; b ; Peter C.K. Leunga ; peter.leung@ubc.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：S1P ; COX-2 ; PGE2 ; YAP ; Granulosa cells
- 刊名：Cellular Signalling
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：28
- 期：6
- 页码：643-651
- 全文大小：1194 K
文摘
- class="listitem" id="list_l0005">
- class="label">•
S1P increases COX-2 expression and PGE2 production in human granulosa cells.
- class="label">•
S1P activates YAP signaling in human granulosa cells.
- class="label">•
S1P1/3 mediates the stimulatory effect of S1P on COX-2 expression.
- class="label">•
YAP mediates S1P-induced COX-2 expression.