Lung function, transfusion, pulmonary capillary blood volume and sickle cell disease
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- 作者：Alan Lunta ; b ; alan.lunt@nhs.net" class="auth_mail" title="E-mail the corresponding author ; Emily McGheea ; emily.mcghee@kcl.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Polly Robinsona ; polly.robinson@gmail.com" class="auth_mail" title="E-mail the corresponding author ; David Reesc ; david.rees2@nhs.net" class="auth_mail" title="E-mail the corresponding author ; Susan Heightc ; sue.height@nhs.net" class="auth_mail" title="E-mail the corresponding author ; Anne Greenougha ; b ; anne.greenough@kcl.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sickle cell disease ; Lung function abnormalities ; Pulmonary capillary blood volume ; Transfusion
- 刊名：Respiratory Physiology & Neurobiology
- 出版年：2016
- 出版时间：1 February 2016
- 年：2016
- 卷：222
- 期：Complete
- 页码：6-10
- 全文大小：395 K
文摘
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Obstructive and restrictive lung function abnormalities occur in SCD children.
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SCD children have increased pulmonary capillary blood volume (PCBV).
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Respiratory system resistance and PCBV were measured before/after transfusion.
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Respiratory system resistance and PCBV significantly increased post transfusion.
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Increased PCBV may partially explain lung function abnormalities in SCD children.