Highly selective determination of amitriptyline using Nafion-AuNPs@branched polyethyleneimine-derived carbon hollow spheres in pharmaceutical drugs and biological fluids
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Synthesis of AuNPs@bPEI-derived carbon hollow spheres.

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Usage of Nafion because of its immobilization matrix capability and cation-exchange properties.

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Usage of Amitriptyline in the treatment of depression, child bedwetting and psychomotor disorders.

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Applicability of proposed modified electrode as amperometric or/and voltammetric sensor.

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The detection limit of the sensor as low as 34 nmol L−1.

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