Use of trimetasphere metallofullerene MRI contrast agent for the non-invasive longitudinal tracking of stem cells in the lung
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- 作者：Sean V. Murphya ; semurphy@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; Austin Halea ; halear0@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Tanya Reida ; tareid@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; John Olsonb ; jdolson3@earthlink.net" class="auth_mail" title="E-mail the corresponding author ; Amritha Kidiyoora ; akidiyoo@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; Josh Tanb ; jtan@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; Zhiguo Zhouc ; zhouz@lunainc.com" class="auth_mail" title="E-mail the corresponding author ; John Jacksona ; jojackso@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; Anthony Atalaa ; aatala@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Magnetic resonance imagining ; Gadolinium ; Contrast agent ; Endohedral metallofullerenes ; Cell tracking ; Lung disease
- 刊名：Methods
- 出版年：2016
- 出版时间：15 April 2016
- 年：2016
- 卷：99
- 期：Complete
- 页码：99-111
- 全文大小：3142 K
文摘
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Trimetasphere® positive contrast agent was evaluated for tracking cells within the lung.
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Cells can be labeled passively without effecting cell viability or proliferation.
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Small numbers of cells can be detected within the lung using MRI.
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High-resolution 3D imaging and tracking can be performed in longitudinal studies.