Changes in the enhancer landscape during early placental development uncover a trophoblast invasion gene-enhancer network
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- 作者：Geetu Tutejaa ; 1 ; Tisha Chunga ; Gill Bejeranoa ; b ; c ; bejerano@stanford.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Trophoblast invasion ; Cis-regulation ; Gene-enhancer network
- 刊名：Placenta
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：37
- 期：Complete
- 页码：45-55
- 全文大小：1361 K
文摘
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A genome-wide in vivo enhancer map from e7.5 and e9.5 placenta is obtained.
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E7.5-specific enhancers are associated with trophoblast invasion genes.
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A transcriptional code is identified in enhancers associated with migration genes.
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A trophoblast invasion gene-enhancer network is constructed.