Transcriptome modifications in human gingival fibroblasts exposed to 2-hydroxyethyl methacrylate
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- 作者：Chiara Di Nisioa ; 1 ; c.dinisio@unich.it" class="auth_mail" title="E-mail the corresponding author ; Marco D'Aurorab ; c ; 1 ; m.daurora@unich.it" class="auth_mail" title="E-mail the corresponding author ; Viviana di Giacomoa ; v.digiacomo@unich.it" class="auth_mail" title="E-mail the corresponding author ; Liborio Stuppiab ; c ; stuppia@unich.it" class="auth_mail" title="E-mail the corresponding author ; Amelia Cataldia ; cataldi@phobos.unich.it" class="auth_mail" title="E-mail the corresponding author ; Valentina Gattab ; c ; v.gatta@unich.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：HEMA ; 2-Hydroxyethyl methacrylate ; HGFs ; Human gingival fibroblasts ; DEGs ; Differentially expressed genes
- 刊名：Gene
- 出版年：2016
- 出版时间：10 May 2016
- 年：2016
- 卷：582
- 期：1
- 页码：38-46
- 全文大小：1148 K
文摘
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HEMA induces transcriptome modulation in cultured human gingival fibroblasts.
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HEMA modulates genes involved in proliferation impairment and apoptosis.
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Short exposure induces repair mechanisms with an early compensatory response.
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Long exposure shows damage accumulation and increased apoptosis.