In silico and in vivo analysis of Toxoplasma gondii epitopes by correlating survival data with peptide-MHC-I binding affinities
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- 作者：Si-Yang Huanga ; b ; Maria Risager Jensenb ; Carina Agerbo Rosenbergb ; Xing-Quan Zhua ; Eskild Petersenc ; Thomas Vorup-Jensenb ; vorup-jensen@biomed.au.dk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Vaccine antigens ; In silico prediction ; MHC class I ; Toxoplasma gondii
- 刊名：International Journal of Infectious Diseases
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：48
- 期：Complete
- 页码：14-19
- 全文大小：1197 K
文摘
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For peptides, the higher the affinity to major histocompatibility complex class I, the better the immunity.
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This study provides a rationale for selecting vaccine epitopes in silico.