Reduction-responsive POEGMA-b-PTPPC6SAM block copolymers were synthesized via RAFT polymerization.
POEGMA-b-PTPPC6SAM block copolymers could self-assemble into spherical micelles and vesicles.
POEGMA-b-PTPPC6SAM micelles had a higher photo-toxicity with a lower IC50 (porphyrin concentration below 3 μg/mL).