A systematic review and meta-analysis was performed to establish the range of reference values of 2DSTE-derived LV strain is children.
The search identified 2,325 children from 43 data sets.
Mean LV GLS value was −20.2%, mean GCS was −22.3%, and mean GRS was 45.2%. LV strain did not vary by age.
LV SLS has a stable apex-to-base gradient that is preserved throughout maturation.