Reference Ranges of Left Ventricular Strain Measures by Two-Dimensional Speckle-Tracking Echocardiography in Children: A Systematic Review and Meta-Analysis
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A systematic review and meta-analysis was performed to establish the range of reference values of 2DSTE-derived LV strain is children.

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The search identified 2,325 children from 43 data sets.

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Mean LV GLS value was −20.2%, mean GCS was −22.3%, and mean GRS was 45.2%. LV strain did not vary by age.

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LV SLS has a stable apex-to-base gradient that is preserved throughout maturation.

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